The Medical Informatics Initiative encompasses multiple regions in Germany. Participating institutes and groups must coordinate their activities, and interact with diverse stakeholders. Various committees have been established to organise structured dialogue and collaboration.

The goal is to ensure that locally developed IT solutions are interoperable with other systems. Furthermore, the new infrastructures must meet very high standards of quality, data protection and security. It is especially important to understand the aims, requirements, and concerns of diverse stakeholders – including scientists, doctors, patients, representatives of regulatory bodies, and many others – and to incorporate these insights into the initiative.

All consortia are represented in the corresponding National Steering Committee, with the aim of aligning activities and agreeing parameters. These shared parameters are developed and discussed in dedicated working groups. During the conceptual phase, these included the groups: consent, data sharing and interoperability.

Additionally, the Dialogue Forum allows representatives from the various groups to exchange ideas and information. Participants include patient advocacy groups, policy makers, government agencies funding organisations, research centres and other scientific institutions, and healthcare IT industry organisations. The forum ensures that strategic planning is discussed, agreed and supported by all stakeholders.

Moreover, collaboration between and beyond consortia is promoted by the coordination office, jointly managed by TMF (Technology, Methods and Infrastructure for Networked Medical Research), MFT (Medizinischer Fakultätentag, an association of German medical faculties), and VUD (Verband der Universtitätsklinika Deutschlands, which represents a number of German university hospitals).